T-cell-directed therapies in systemic lupus erythematosus.
نویسندگان
چکیده
Drug development for the treatment of systemic lupus erythematosus (SLE) has largely focused on B-cell therapies. A greater understanding of the immunopathogenesis of SLE coupled with advanced bioengineering has allowed for clinical trials centered on other targets for SLE therapy. The authors discuss the benefits and shortcomings of focusing on T-cell-directed therapies in SLE and lupus nephritis clinical trials.
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ورودعنوان ژورنال:
- Lupus
دوره 25 10 شماره
صفحات -
تاریخ انتشار 2016